Sakitamiwa - Classification

💡 Doctors use this system to determine if a treatment—like proton pump inhibitors (PPIs) —is working. An ulcer is medically considered "cured" once it reaches the S1 or S2 stage.

It provides an objective endpoint for measuring ulcer healing rates in clinical trials, such as comparing the effectiveness of different Proton Pump Inhibitors (PPIs).

, the final stage in the healing process, is called the "White Scar" (或白色瘢痕期) . Over a period ranging from several months to a few years, the intense redness of the S1 scar gradually fades as the vascularity decreases and the tissue matures. Eventually, the color of the scar tissue returns to the same shade as the surrounding, healthy mucosa. At this point, the ulcer is considered fully healed endoscopically. sakitamiwa classification

The regenerating epithelium completely covers the ulcer floor, and the white coating has disappeared. The area appears markedly red due to the presence of many new capillaries.

This final stage indicates that the ulcer has closed, though the underlying tissue is still maturing. 💡 Doctors use this system to determine if

| Feature | Group I (Primarily Pulmonary) | Group II (Extra-Pulmonary) | | :--- | :--- | :--- | | | Lungs / Thoracic cavity | Outside the lungs (nodes, brain, bones) | | Pathophysiology | Localized primary complex | Hematogenous dissemination | | Radiology | Hilar adenopathy, lung infiltrates | Often normal lung X-ray (unless miliary) | | Contagiousness | Low (children usually paucibacillary) | None (unless concomitant pulmonary TB) | | Example | TB Lymphadenitis (Hilar) | TB Meningitis, Scrofula (Neck) |

The strength of the lies in its predictive power. A 2021 multicenter retrospective study involving 1,200 patients found that: , the final stage in the healing process,

The scarring stage represents the successful resolution of the ulcer, where the open wound is entirely replaced by new structural tissue.